Polio: Causes and Effects, Part I

September 7, 2010 by
Filed under: Vaccine Science, Vaccine/Disease Analysis 

We saw in our first [1] blog on polio that infection with this virus was common, but paralytic polio was rare. In our second [2] article we reviewed the history of polio and the significant number of cases of paralysis from other causes which were blamed on polio. In the third [3] article we looked at one of the explanations for the rise of paralytic polio in advanced countries and the collapse of this explanation as polio increased in developing countries.

With polio, is there one cause, the virus, and one effect, paralysis? Obviously not, as the results of infection with the polio virus range from absolutely nothing to death. In this series we are going to review some of the factors which, combined with the presence of the virus, can move the situation from no symptoms and no problems, to paralysis.

A characteristic of infection with polio is the length of time it takes to clear the virus from the body and create immunity to polio.

…the interval between initiation of infection and appearance of CNS signs may be as long as several weeks, which accounts for the great variation in the incubation period of the disease. [4]

CNS means inflammation of the central nervous system. Someone can be carrying around a happily multiplying polio virus in the nose, throat and gut system, and other non-neural areas of the body, for a period of weeks without having any symptoms to indicate that the virus is there. “Non-symptomatic response” to polio virus exposure, results in eventual clearing of the virus from the system, permanent immunity to that strain of polio, and is the normal bodily response to the polio virus.

However, if something occurs during the several weeks of polio virus carriage which opens up access to the central nervous system to the virus, then the polio moves from asymptomatic to paralytic. There is a list of provokers which cause polio to invade the CNS.   Today we are going to consider one cause which we can credit to the medical profession.

Provocation polio due to vaccines or other injections:  the third item on the chart of types of acute flaccid paralysis is “vaccine-associated paralytic poliomyelitis.” [5]  Yes, vaccines can cause paralytic polio. In fact  injections of many different drugs such as anesthetics, antibiotics, etc, can cause paralytic polio.

A study which clearly demonstrates this phenomena and which changed vaccination practices in the U.S. is here [6]:

This investigation corroborates the published findings of other investigators that there is a relationship between recent inoculation with diphtheria toxoid, tetanus toxoid or pertussis vaccine (DPT) and the development of paralytic poliomyelitis. This is indicated by the fact that a significantly larger percentage of children was paralyzed in the injected limb when the last injection had been received not more than a month preceding onset of poliomyelitis than when received from a month to a year before.

Other injections can also provoke paralysis from the virus.

…enhanced risk of paralytic manifestations that follows intramuscular injection, and it occurs when inflammation in muscle coincides with poliovirus infection; entry of poliovirus to nerve endings in the muscle is facilitated, and paralysis occurs 4—30 days later. [5]

The oral polio vaccine is also associated with paralytic poliomyelitis.  The role of intramuscular injections in the Romania polio outbreak resulted in an extremely high number of cases of vaccine associated polio:

The strength of the association between intramuscular injections and vaccine-associated paralysis was similar for the vaccine recipients and the children who acquired the disease by contact, as was the dose-response effect. For cases in vaccine recipients, the timing of intramuscular injections with respect to the receipt of OPV was critical; injections administered after the receipt of OPV, but not before or at the same time as OPV, were associated with elevated risk. In addition, our finding are similar to observations in the late 1940s and 1950s that intramuscular injections have a tendency to “provoke” paralysis in the injected limbs of persons infected with wild-type poliovirus. This association was particularly noticeable in the United Kingdom, where DTP was injected into the arm and there was a reversal in the ratio of arm involvement to leg involvement among children with paralytic poliomyelitis. (emphasis added) [7]

While this information was readily available in the literature. children in Romania suffered unnecessary paralysis from 1970  until nearly 1995,  (around 25 years) because scientists were seemingly incapable of reading their own literature and spotting a known and obvious explanation for the problem.

The historical increase in polio in western countries, as we saw in our last article, was blamed on improved sanitation, one of many factors which change when developing countries modernize. Another overlooked factor, despite the extensive documentation in the scientific literature, is the arrival of injections with western medicine. For example, Samoan children ended up with paralysis from injections against yaws:

The 1936 report by Lambert of a severe epidemic of paralytic polimyelitis among Samoan children inoculated with neoarsphenamine for yaws provides a good example not only of one way in which “civilization” may contribute to the increase of paralytic poliomyelitis, but perhaps also one of the earliest incidents suggesting the role of inoculations at a time when a virulent virus is widespread. The Samoans believe that the neoarsphenamine injections were responsible for the paralysis, while Lambert and his associates thought it was pure accident, since the disease was typical of poliomyelitis. [8]

In the U.S. vaccinations were introduced very gradually from 1900 to 1940, when the pace picked up. [9] With each increase in the use of vaccination (and other injected medications) came increased opportunities for vaccine provoked polio.

Articles in the medical literature indicate that provocation paralysis continues to occur, from the combination of OPV and subsequent intramuscular injections and from the use of injections in areas where the polio virus is still circulating.  The inability of doctors and scientists to read and comprehend their own scientific literature continues to cause cases of paralysis.

Examples of provocation polio:

Provocation of poliomyelitis occurred in 66% of children and usually followed intragluteal injections associated with treatment of non-specific fevers…The risk factors identified in our study are lack of immunization and administration of intramuscular injections during the pre-paralytic phase. [ 10]

and an outbreak in 1999-2000 shows that the beat of unnecessary paralysis moves on and on.

With little difference in the vaccination status of cases and controls, the only clear risk factor for type 3 poliomyelitis in this study was having at least one injection in the month prior to paralysis onset. [11]

Injections are an immensely popular form of medical treatment in developing countries and delivered not just by trained personnel but by traditional healers and by family members. As we outlined in our article Medical Double Standards in the Third World, carelessness with needles means that millions of reusable needles are available to people with no clear idea of how to use them safely or appropriately. As shown above, even medical personnel seem to be unclear on the dangers of giving injections in the month following a dose of the oral polio vaccine, or when poliomyelitis is circulating in the community. Vaccine provoked poliomyelitis has not ended and may not end for many years to come. After all, letting the general population know that injections are dangerous might keep people from getting their good shots:

In planning to reduce the number of unnecessary injections it is important to avoid negative effects on people’s perceptions of vaccinations and contraceptive injections. [12]

Misinformation about the potential danger of vaccinations is a worldwide problem.

For more information on provocation polio: Mechanism of Injury-Provoked Poliomyelitis, Matthias Gromeier and Eckard Wimmer. Journal of Virology, June 1998, p. 5056-5060. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC110068/pdf/jv005056.pdf

[1] Polio 2010. Inside Vaccines. May 26, 2010. http://insidevaccines.com/wordpress/2010/05/26/polio-2010/

[2] Polio and Acute Flaccid Paralysis. Inside Vaccines. June 2, 2010. http://insidevaccines.com/wordpress/2010/06/02/polio-and-acute-flaccid-paralysis/

[3] Polio and Sanitation. Inside Vaccines. July 1, 2010. http://insidevaccines.com/wordpress/2010/07/01/polio-and-sanitation/

[4] Epidemiology of Poliomyelitis and Allied Diseases – 1963. Dorothy M. Horstmann. The Journal of Biology and Medicine, 1963, 36, 5-26. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2604573/pdf/yjbm00599-0011.pdf

[5] Differential Diagnosis of Acute Flaccid Paralysis and Its Role in Poliomyelitis Surveillance, Arthur Marx, Jonathan D. Glass, and Roland W. Sutter. Epidemiologic Reviews, Vol. 22, No. 2, 2000 http://epirev.oxfordjournals.org/cgi/reprint/22/2/298.pdf

[6] The Relation Between Recent Injections and Paralytic Poliomyelitis in Children. Morris Greenberg, Harold Abramson, Helen M. Cooper and Helen E. Solomon. American Journal of Public Health, 1952, 42, 142-152. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1525737/pdf/amjphnation00407-0031.pdf

[7] Intramuscular Injections Within 30 Days of Immunization with Oral Poliovirus Vaccine – A Risk Factor for Vaccine-Associated Paralytic Poliomyelitis. Peter M. Strebel, Nicholae Ion-Nedelcu, Andrew L. Baughman, Roland W. Sutter, and Stephen I. Cochi. New England Journal of Medicine, 1995, 332, 8, 500-506.  http://www.nejm.org/doi/pdf/10.1056/NEJM199502233320804

[8] Paralytic Consequences of Poliomyelitis Infection in Different Parts of the World and in Different Population Groups, Albert B. Sabin, American Journal of Public Health, Vol. 41, Oct. 1951. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1525657/pdf/amjphnation00428-0010.pdf

[9]Historic Dates and Events Related to Vaccines and Immunization. Accessed on September 12, 2010. http://www.immunize.org/timeline/

[10] Poliomyelitis: 20 years–the Pondicherry experience. Mahadevan S, Ananthakrishnan S, Srinivasan S, Nalini P, Puri RK, Badrinath S, Rao RS. The Journal of Tropical Medicine and Hygiene. 1989 Dec;92(6):416-21. http://www.ncbi.nlm.nih.gov/pubmed/2558226

[11] Outbreak of poliomyelitis due to type 3 poliovirus, northern India, 1999–2000: injections a major contributing factor. Kathryn A Kohler, W Gary Hlady, Kaushik Banerjee and Roland W Sutter, International Journal of Epidemiology, 2003, 32, 272-277. http://ije.oxfordjournals.org/content/32/2/272.full.pdf+html

[12] Anthropological Perspectives on Injections: A Review. A. V. Reeler. Bulletin of the World Health Organization, 2000, 78, 135-143. http://www.who.int/bulletin/archives/78%281%29135.pdf

Comments

12 Comments on Polio: Causes and Effects, Part I

  1. Gold-DNA on Sat, 18th Sep 2010 12:01 pm
  2. Great article, as usual. Unfortunately you cannot read my view reagarding polio, because it is written in German, available under http://www.gold-dna.de/polio.html. Polio has a close relation to environmental toxins, low blood sugar, malaria and some other parameters. The virus is not the cause, it is the result of environmental influences.
    I hope you keep going, as I am looking forward to every new article.

    Gold-DNA

  3. admin on Sat, 18th Sep 2010 1:29 pm
  4. Hi Gold,
    Funny but one of our members reads German. I’ll pass the link on and see if your research is helpful. Thanks for the kudos and the link.

  5. noftm on Fri, 22nd Oct 2010 12:09 pm
  6. I am slowly making my way through your website, so if this is answered elsewhere, forgive me. But would “injection-based infections” happen not only with polio but with other viruses as well?

    If you can provoke polio, can’t you provoke any other virus that the individual may have been exposed to? Hypothetically speaking, what if autism is a result of a viral infection that is provoked by the increased vaccine schedules of children? Maybe this is why no one has pin pointed it to a particular vaccine.

  7. admin on Fri, 22nd Oct 2010 6:52 pm
  8. Interesting question. insidevaccines tries to stick to the published literature, where vaccine provoked polio is well-documented. I don’t know if other viruses have been studied. I’ll put it up to our research team.

  9. admin on Mon, 25th Oct 2010 5:52 am
  10. noftm,
    Took your question back and we talked it over. In the case of polio, the virus is already present and the injection opens up access to the nervous system. I’m doubtful that there are other viruses (outside of the those related to polio) where injections would have similar results.

    So no, that is interesting, but probably not what is going on.

  11. Katie B on Mon, 8th Nov 2010 7:22 pm
  12. My father got paralytic polio when living in Italy in 1961. he was 25 years old and a fit, healthy young man. What do you think might have caused it? (BTW, he was unvaccinated).

  13. Peter on Tue, 18th Jan 2011 9:37 am
  14. In a very informative article from Thinktwice.com you will find among others additional literature for the connection between inoculation and paralysis in children

    link to the article: http://thinktwice.com/Polio.pdf

  15. admin on Tue, 18th Jan 2011 6:16 pm
  16. Thank you!

    [...] traducción para Disiciencia del artículo Polio: Causes and Effects, Part I de insidevaccines.com Like this:LikeBe the first to like this post. By Disiciencia, on 15/03/2012 [...]

  17. greek one on Wed, 1st Aug 2012 10:25 pm
  18. katie b.. how do you know your father was fit and healthy.. did he get blood work??? was he severly deficient in vital nutrients.. was there another undetected health issues.. your guessing your father was fit and healthy.. and so was he.. but that does not mean we shoudl delibrately sacrifice children to die from and become chronically ill from vaccines?? where does the other half of the population get off thinking they have a right to bully or intimidate all these injections into others bloodstream??? i think that the cult of vaccine is just becoming such a bizzare and barbaric culture.. people are really good at hiding behind thier fears.. you should really not be afraid of the light and learn something.. we are not likely to get all the diseases we vaccinate for.. then i ask.. when there is no natural immunity to pass down how will the immune systems of the next generations fair.. dependant on synthetic chemicals and managing chronic disesase and cancer.. autoimmune disease… vaccines are destructive and decieving and the most innocent of our population is made to suffer.. how dare anyone coerce or manipulate or mandate others be forcibly or coercivly injected with anything the pharma people can package in a vaccine… what is wrong with everyone??? it’s like the world has gone made.. no longer is there respect or boundaries.. it’s immoral.. if you are so afraid of disease don’t project it on me by forcing this barbaracey.. go live in a goddamnned bubble.. and take your crappy vaccines with you… if my child were to start siezing because i vaccinated again.. i can’t undo it.. nor can i sue the vaccine company… and with any vaccine there is a risk of death.. how dare anyone force me to put this on my child… i have a friend with a liver transplant , autistic neighbor, cousins, and neurologically damaged family members, enough with the mandates and bullying.. this society is completely insane

  19. Peter on Fri, 5th Oct 2012 4:23 am
  20. This one is interesting too http://www.ncbi.nlm.nih.gov/pubmed/12929860

    Natl Med J India. 2003 May-Jun;16(3):156-8.
    Diagnosis of acute flaccid paralysis: injection injury or polio?
    Wyatt HV.
    Source

    School of Healthcare Studies, University of Leeds, Leeds LS2 9UT, England. nurhvw@leeds.ac.uk
    Abstract

    In many countries, the treatment of choice for all fevers is one or more injections. These injections are associated with a risk of nerve damage. If cases of poliomyelitis are not to be missed, the diagnosis of injection trauma or traumatic neuritis (TN) must be exact. The guides for distinguishing between TN and polio are not clear. It is probable that some cases of polio are misdiagnosed as TN. As three-quarters of children with paralytic polio receive injections just before the onset of paralysis, their paralysis may be mistaken for TN. Clearer guidelines are proposed, together with suggestions for better documentation of muscles injected and paralysed. All cases of reported TN should be monitored and new diagnostic guidelines published. To protect their children, mothers must be educated to understand that injections for fever can cause harm. This must be an important part of the eradication programme for poliomyelitis.

  21. Boss on Fri, 5th Oct 2012 5:58 am
  22. What is utterly horrifying is that this problem has been clearly identified for over 50 years and yet the doctors are still provoking paralysis with injections.

    Thanks for the article!

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