H1N1 Influenza in the U.S.
While it’s too soon to be sure, influenza numbers are dropping and the season may be coming to an early close. The CDC has these numbers:
During week 51 (December 20-26, 2009), influenza activity decreased slightly in the U.S.
154 (3.9%) specimens tested by U.S. World Health Organization (WHO) and National Respiratory and Enteric Virus Surveillance System (NREVSS) collaborating laboratories and reported to CDC/Influenza Division were positive for influenza.
Translation: of thousands of tested cases of “might be flu”, 154 turned out to really be flu, only 3.9% of the total specimens tested. Lots of sneezing and coughing out there, and not an insubstantial number of hospitalizations and deaths for “influenza-like-illness and pneumonia” , but no influenza viruses are the main cause at this point.
2009 H1N1 virus did turn out to be more dangerous to children than the typical yearly influenza virus: the CDC received 225 reports of deaths this year, 130 last year, 88 in 2007 and 78 in 2006.
The breakdown by age:
Since August 30, 2009, CDC has received 225 reports of influenza-associated pediatric deaths that occurred during the current influenza season (42 deaths in children less than 2 years old, 25 deaths in children 2-4 years old, 83 deaths in children 5-11 years old, and 75 deaths in children 12-17 years old).
How likely was a child under 2 to die from H1N1 based on these numbers?
Live births in 2007: 4,317,000, minus 29,000 infant deaths, gives us a starting number of 4,288,000. The number of births has been going up every year for the last few years, so if we assume the same number in 2008 we are erring on the side of caution. We’ve got a total of roughly 8,576,000 children in the U.S. under the age of two. Forty-two of those children died this year as a result of H1N1, according to the CDC. This means that one child out of every 204,190 died from 2009 H1N1 according to the reported number of cases.
Are the reported number of cases reflective of the true burden of illness? Probably not entirely, but in November, CBS news reported that:
It’s a little counter intuitive,” Frieden said, “but the best way to estimate the total burden of illness is not to count the cases, but to estimate them based on the best available science.”
However, Ashton pointed out, things are very different when reporting pediatric flu deaths. She said states are required to document each case with the CDC, and every week the updated numbers are an accurate reflection of the entire country.
The numbers of pediatric deaths from 2009 H1N1 are based, therefore, on actual case counts in the U.S., during 2009.
Infants and toddlers were one of the groups recommended for the 2009 H1N1 vaccine. However, if saving the maximum number of lives is our goal, then there are several other causes of death in infants and toddlers which we feel should be addressed with a vigor to match the actual death and injury rates for each category.
Among 1- to 4-year-old children, injuries accounted for 42 percent of all deaths, followed by deaths due to congenital malformations (birth defects), malignant neoplasms (cancer), homicide, and diseases of the heart.
Or to give some comparative numbers:
More than 16,500 lives could be saved each year in the United States alone if our under-5 mortality rate was the same as Iceland. If the U.S. rate of under-5 mortality was similar to that of France, Germany and Italy (all 4 per 1,000 live births), over 12,000 child lives could be spared.
The causes of child deaths in the industrialized world differ dramatically from those in developing countries. In the developing world, over half of under-5 deaths are caused by pneumonia, diarrhea or newborn conditions. In the industrialized world, these problems rarely lead to death. Children’s deaths are most likely the result of injury suffered in traffic accidents, intentional harm, drowning, falling, fire and poisoning.
Mumps Vaccine: Perceptions and Emerging Realities
Mumps outbreaks are occurring in highly vaccinated populations and this has led to differences in opinion amongst scientists around the efficacy of the vaccine, with various mechanisms of failure being put forward. It has been suggested that the number of vaccinated young adults (18-24 yrs) who contracted mumps in the US in 2006 form a small percentage of the overall vaccinated population. The fact that 84% were vaccinated with two doses is reduced to a minor detail when numbers are crunched in the “right” way. However, this is not the view of all scientists. There is concern as to why highly vaccinated populations are having mumps outbreaks. By choosing to avoid the issue, essentially ignoring the reason why young adults who have been vaccinated twice with the MMR are coming down with mumps, the evidence on the real efficacy of mass vaccination against a benign childhood disease is not discussed. Read more
Merck staph vaccine enters phase II
From Forbes:
VIENNA, Aug 28 (Reuters) – Austrian biotech firm Intercell <ICEL.VI> said on Thursday its partner Merck & Co <MRK.N> has started a Phase II clinical trial to evaluate a vaccine candidate against Staphylococcus aureus infections.
Merck is responsible for clinical development, manufacturing and marketing of the vaccine. Intercell is eligible to receive milestone payments and royalties on future net sales
This is the second trial start following a separate Phase II trial launch in December 2007. Read more
Health Marketing, Risk Communication, and the Media
Remember the Great Influenza Vaccine Shortage a few years back?
Panic swept the nation after the FDA rejected many European flu shots because of possible contamination during manufacturing. What was left was rationed according to age and risk factors, and the public could be seen every night on the news waiting in long lines to get the remaining doses.
Now, setting aside for the moment the ongoing questions regarding the usefulness of flu shots in any age group, especially the elderly, one might come to wonder what has changed in recent years to bring about this new terror regarding influenza.
The answer, as outlandish and implausible as it might sound, is that this fear has been manufactured and marketed by the people in public health. Read more
Where Do They Find These Scary Statistics?
Filed under: CDC Watch, News, Vaccine Science, Vaccine/Disease Analysis
Dr. Gerberding of the CDC
[Series Links: Part II, Part III]
Remember Hannah Poling? The head of the CDC, dressed in a very nice pink suit, appeared on TV and discussed Hannah’s case. In one of her appearances she said something like this: “Vaccines prevent 33,000 deaths a year in the United States.” Just to make sure I had the statement right, I searched for the phrase and found it again, from CNN, this time in print.
Today, through immunizations given in the first two years of life, we can protect children from 16 diseases, preventing 33,000 deaths and 14 million illnesses per year.
A few searches made it clear that this is a very popular statistic. A variety of news stories included the information that vaccines prevent 33,000 deaths a year in the United States. This is an interesting number to anyone who knows a bit about the history of infectious diseases. I decided to dig deeper.
My next find was this chart, which is on a the web-site of an organization called Every Child by Two. The chart provides morbidity (incidence) and mortality (deaths) for each disease. How in the world would someone be able to calculate (for example) the exact number of cases of diphtheria which would occur and the exact number of deaths which would follow? Amazing! There must be some truly extraordinary scientific research underlying these numbers, don’t you think? Read more
MRSA and Child Flu Deaths
Recent news stories about a link between MRSA and flu deaths in children raise some interesting questions in light of our Sisyphus series (Part I, Part II and Part III).
“Being a carrier of MRSA has increased a lot, especially among school-aged kids,” said Lyn Finelli, chief of influenza surveillance at the CDC. “And being colonized may put them at risk for a severe staph aureus infection when they get the flu.”
This particular news story blames the problem on antibiotic overuse, and, of course, recommends the flu vaccine to save children from this dangerous situation. Read more
Happy May 1st!
Insidevaccines is three months old today. In three months our team of writers, editors and proofreaders have put together 23 articles. In the days just before our opening on February 1st we also compiled 22 pages of useful information on a wide variety of vaccine related topics. We have linked to published scientific papers, to the Centers for Disease Control and to manufacturer’s product inserts.
We would like to thank all of the people who have spread links to insidevaccines across the web, with special thanks to Sandy Gottstein of Vaccination News and Ginger Taylor of Adventures in Autism for adding our link to their sites.
Disclaimer: Insidevaccines, although it is three months old, has not yet received any of the CDC recommended vaccines. Enter at your peril!